Package: STACAS Type: Package Title: STACAS: Sub-Type Anchoring Correction for Alignment in Seurat Version: 2.4.1 Authors@R: c( person(given = 'Massimo', family = 'Andreatta', email = 'massimo.andreatta@unil.ch', role = c('aut','cre'), comment = c(ORCID = '0000-0002-8036-2647')), person(given = 'Ariel', family = 'Berenstein', email = 'arieljberenstein@gmail.com', role = c('aut'), comment = c(ORCID = '0000-0001-8540-5389')), person(given = 'Josep', family = 'Garnica', email = 'Josep.Garnicacaparros@unige.ch', role = c('aut'), comment = c(ORCID = '0000-0001-9493-1321')), person(given = 'Santiago', family = 'Carmona', email = 'santiago.carmona@unil.ch', role = c('aut'), comment = c(ORCID = '0000-0002-2495-0671')) ) Description: This package implements methods for batch correction and integration of scRNA-seq datasets, based on the popular Seurat anchor-based integration framework. In particular, STACAS is optimized for the integration of heterogenous datasets with only limited overlap between cell sub-types (e.g. TIL sets of CD8 from tumor with CD8/CD4 T cells from lymphnode), for which the default Seurat alignment methods would tend to over-correct biological differences. The 2.0 version of our package allows to the users to incorporate explicit information about cell-types in order to assist the integration process. biocViews: Depends: R (>= 4.0.0) Imports: Seurat(>= 5.0.0), SeuratObject(>= 5.0.0), data.table, pbapply, ggridges, colorspace, R.utils, ggplot2, stats, BiocNeighbors, BiocParallel Suggests: testthat (>= 3.0.0), sf License: GPL-3 + file LICENSE Encoding: UTF-8 LazyData: false RoxygenNote: 7.3.2 Config/testthat/edition: 3 Config/pak/sysreqs: cmake libglpk-dev make libicu-dev libpng-dev libuv1-dev libxml2-dev libssl-dev python3 zlib1g-dev Repository: https://carmonalab.r-universe.dev Date/Publication: 2026-01-27 09:46:28 UTC RemoteUrl: https://github.com/carmonalab/STACAS RemoteRef: HEAD RemoteSha: ea34e824e17df6316823db0a9b6322af0833e501 NeedsCompilation: no Packaged: 2026-05-27 06:44:53 UTC; root Author: Massimo Andreatta [aut, cre] (ORCID: ), Ariel Berenstein [aut] (ORCID: ), Josep Garnica [aut] (ORCID: ), Santiago Carmona [aut] (ORCID: ) Maintainer: Massimo Andreatta