Package: scTypeEval Title: Evaluation of cell type classifications in single-cell transcriptomics Version: 1.1.1 Authors@R: c( person(given = 'Josep', family = 'Garnica', email = 'josep.garnicacaparros@unige.ch', role = c('aut', 'cre'), comment = c(ORCID = '0000-0001-9493-1321')), person(given = 'Massimo', family = 'Andreatta', email = 'massimo.andreatta@unige.ch', role = c('aut'), comment = c(ORCID = '0000-0002-8036-2647')), person(given = 'Santiago', family = 'Carmona', email = 'santiago.carmona@unige.ch', role = c('aut'), comment = c(ORCID = '0000-0002-2495-0671')) ) Description: scTypeEval provides tools to evaluate and validate cell type classifications in single-cell transcriptomics when ground truth labels are limited or unavailable. Results are organized in an S4 object that integrates processed data, dimensional reductions, dissimilarity assays, and consistency metrics computed across samples. The workflow includes preprocessing and feature selection, principal component analysis, computation of dissimilarity matrices, internal validation metrics (for example, silhouette-based summaries), and visualization utilities to inspect heatmaps and PCA plots. Functions support common single-cell containers and enable comparison of clustering and labeling strategies across datasets. Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 8.0.0 VignetteBuilder: knitr URL: https://github.com/carmonalab/scTypeEval BugReports: https://github.com/carmonalab/scTypeEval/issues License: GPL-3 + file LICENSE LazyData: false biocViews: SingleCell, Transcriptomics, GeneExpression, CellBasedAssays, DimensionReduction, Preprocessing, PrincipalComponent Depends: R (>= 4.6.0) Imports: Matrix (>= 1.6-5), BiocParallel (>= 1.34.2), dplyr (>= 1.1.4), tidyr (>= 1.3.1), scran (>= 1.30.2), bluster (>= 1.12.0), ggplot2 (>= 3.5.1), ggrepel (>= 0.9.6), cluster (>= 2.1.4), SingleR (>= 2.4.1), irlba (>= 2.3.5.1), transport (>= 0.15-4), grDevices, methods, stats, utils Suggests: testthat (>= 3.0.0), transformGamPoi (>= 1.8.0), glmGamPoi (>= 1.14.3), anndata (>= 0.8.0), SummarizedExperiment (>= 1.32.0), igraph (>= 2.1.1), Seurat, SingleCellExperiment, knitr, rmarkdown, BiocStyle, BiocManager, SeuratObject, ggpubr, rlang, stringr, tibble Config/testthat/edition: 3 Config/pak/sysreqs: libglpk-dev libicu-dev libxml2-dev zlib1g-dev Repository: https://carmonalab.r-universe.dev Date/Publication: 2026-06-24 07:44:28 UTC RemoteUrl: https://github.com/carmonalab/scTypeEval RemoteRef: HEAD RemoteSha: 9ec56f727a4698c24350e7e1ebec524ea438a61b NeedsCompilation: no Packaged: 2026-06-24 10:24:49 UTC; root Author: Josep Garnica [aut, cre] (ORCID: ), Massimo Andreatta [aut] (ORCID: ), Santiago Carmona [aut] (ORCID: ) Maintainer: Josep Garnica